Scientists have discovered a human antibody that is said to be effective in potentially preventing SARS-CoV-2 infection-causing Covid-19.

Scientists have discovered a human antibody that is said to be effective in potentially preventing SARS-CoV-2 infection-causing Covid-19.

The health researchers from the University of Massachusetts Medical School (UMMS) in the US have discovered and characterised a cross-reactive human monoclonal antibody to SARS-CoV-2 spike proteins which block ACE2 receptor binding on the mucosal tissue of the respiratory tract.

The origins of this discovery went back to 16 years, when health scientists at UMMS developed an IgG monoclonal antibody that was effective against a similar virus, SARS, reported the study published in the journal Nature Communications.

Health experts say that the first MAB might help with this new infection. They launched the process of resurrecting the old SARS programme, retrieving frozen cells that had been developed 16 years earlier, thawing them and determining if what worked for one novel coronavirus would work for another.

Although there was 90 per cent similarity between the two coronaviruses, the monoclonal antibody exhibited no binding to the current coronavirus, the researchers said.


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